J. B. Hedges, J. A. Marchand, C. Calvó-Tusell, D. C. Millar, M. Garcia-Borràs, M. C. Y. Chang, K. S. Ryan
"Terminal Alkyne formation by a pyridoxal phosphate-dependent enzyme"
Nature Chemical Biology - In Press (2025).
Embedded Files
Hinako Kawabe, Luran Manfio, Sebastian Magana Pena, Nicolette A. Zhou, Kevin M. Bradley, Cen Chen, Chris McLendon, Steven A. Benner, Karen Levy, Zunyi Yang, Jorge A. Marchand, Erica R. Fuhrmeister
ACS Synthetic Biology (2024).
E. Kuru, J. Rittichier, H. de Puig,Isaac Han, A. Flores, A. E. Reese, T. M. Bartlett, F. De Moliner, S. Rout, S. Bernier, J. D. Galphin, J. A. Marchand, W. Bedell, L. Robinson-McCarthy, C. A. Ahern, T. G. Bernhardt, D. Z. Rudner, J. J. Collins, M. Vendrell, G. M. Church
"Rapid discovery and evolution of nanosensors containing fluorogenic amino acids"
Nature Communications (2024).
Hinako Kawabe, Christopher A Thomas, Shuichi Hoshika, Myong-Jung Kim, Myong-Sang Kim, Logan Miessner, Nicholas Kaplan, Jonathan M Craig, Jens H Gundlach, Andrew H Laszlo, Steven A Benner, Jorge A Marchand
"Enzymatic synthesis and nanopore sequencing of 12-letter supernumerary DNA"
Nature Communications (2023).
Akos Nyerges, Svenja Vinke, Regan Flynn, Siaan V Owen, Eleanor A Rand, Bogdan Budnik, Eric Keen, Kamesh Narasimhan, Jorge A Marchand, Maximilien Baas-Thomas, Min Liu, Kangming Chen, Anush Chiappino-Pepe, Fangxiang Hu, Michael Baym, George M Church
"Swapped genetic code blocks viral infections and gene transfer"
Nature (2023).
Eli N Kissman, Monica E Neugebauer, Kiera Sumida, Cameron V. Swenson, Nicholas A Sambold, Jorge A Marchand, Douglas C Miller, Michelle C Y Chang.
PNAS (2023).
Pre-2022
Monica E Neugebauer, Eli N Kissman, Jorge A Marchand, Jeff G Pelton, Nicholas A Sambold, Douglas C Miller, Michelle C Y Chang.
"Reaction pathway engineering converts a radical hydroxylase into a halogenase"
Nature Chemical Biology (2021).
Jorge A Marchand , Merrick D Pierson Smela, Thomas H H Jordan, Kamesh Narasimhan, George M Church.
"TBDB – A database of structurally annotated T-box riboswitch:tRNA pairs"
Nucleic Acids Research (2020).
Pei-Hsun Wu, Daniele M Gilkes, Jude M Phillip, Akshay Narkar, Thomas Wen-Tao Cheng, Jorge A Marchand, Meng-Horng Lee, Rong Li, Denis Wirtz
"Single-cell morphology encodes metastatic potential"
Science Advances (2019).
Monica E Neugebauer, Kiera H Sumida, Jeffrey G Pelton, Jonathan L McMurry, Jorge A Marchand, Michelle CY Chang
"A family of radical halogenases for the engineering of amino-acid-based products"
Nature Chemical Biology (2019).
Jorge A Marchand, Monica E Neugebauer, Madeleine C Ing, Chia-I Lin, Jeffrey G Pelton, Michelle CY Chang
"Discovery of a pathway for terminal-alkyne amino acid biosynthesis"
Nature (2019).
Shyam B Khatau, Ryan J Bloom, Saumendra Bajpai, David Razafsky, Shu Zang, Anjil Giri, Pei-Hsun Wu, Jorge A Marchand, Alfredo Celedon, Christopher M Hale, Sean X Sun, Didier Hodzic, Denis Wirtz
Scientific Reports (2013).
Patents
MCY Chang, JAM Benmaman, ME Neugebauer
"Biosynthesis of bioorthogonal amino acids"
US Patent App. 16/600,502 (2019).
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